Description:
The rapidly evolving field of cancer biology is forever changing the way we diagnose and treat bone and soft tissue sarcomas.
This book integrates and summarize the most important clinical, molecular, and therapeutic aspects of pediatric bone and soft tissue sarcomas.
This book highlights the paths leading to the emergence of a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.
This is a comprehensive textbook on bone and soft tissue sarcomas of childhood, adolescence, and young adulthood. It includes information from pediatric oncologists and radiation oncologists, pathologists, diagnostic imaging specialists, and basic scientists from 12 institutions in the United States.
The book serves to integrate the most recent advances in the diagnosis and treatment of pediatric bone and soft tissue sarcomas. It is a welcome addition to the current medical literature on pediatric solid tumors.
The book is divided into two major sections. The first deals with epidemiology, imaging and molecular biology, and principles for drug development. The second section describes diagnosis, treatment, and late effects of therapy. The evidence-based content is rich with details. A multidisciplinary, integrative approach is emphasized throughout. Each chapter starts with a well-organized table of contents that guides the reader through the material. Grasp of information is facilitated by colorful cartoon drawings of gene re-arrangements and function, micro-array data, photomicrographs, and diagnostic images. Figure legends are particularly descriptive and clear. Tabular display of information and an up-to-date, alphabetized bibliography at the end of each chapter facilitate readability. The scholarly review of the molecular biology of bone and soft tissue cancers is probably the strongest element of the book.
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